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ACES researchers randomly assigned 4,012 men and women either once-weekly doses of azithromycin or a placebo for one year, beginning in 1999. After an average follow-up of 3.9 years, there was no significant reduction of cardiac events such as death, myocardial infarction, unstable angina, angioplasty or cardiac surgery defined among participants receive antibiotics compared to patients on placebo. This lack of antibiotic effect was shown for all participants, regardless of age, gender, smoking status, or the presence of C. Pneumoniae antibody. The antibiotic treatment also had no effect on total mortality or on incidence of stroke.T cells need to dendritic cell, tell them thing to do. The study , we show that MKP – 1 signaling by dendritic cells of innate and acquired immune responses immune response bypassed by the scheme cytokines output .. MKP-1 is the first a signal molecule by dendritic cells programmed about differentiation of the varying T cell subgroups found in, said Chi. Saint other scientists concentrated in T -cell differentiation to response to the stimulation via cytokines. Current research crowded a gap in our understanding into dendritic cell – mediated control of T-cell – line of decision, said Chi.
St. Considered essential for the maintaining balanced Immune Response Corporation Identified.
Investigator were surprised to be a single molecule of controlled production of three of four major subsets of T – cells playing different roles. MKP-1 is a negative regulator of said enzyme p38 that are part of MAP kinasis family of enzymes which control means in the cell proliferation, differentiation, and died is involved.